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Description

Cell membrane-associated GR has recently been shown to directly mediate fast feedback inhibition by inhibition of Src phosphorylation in corticotrophs (210), but other work implicates the GC-induced secretion of annexin 1/lipocortin1 from folliculostellate cells as a paracrine mechanism for inhibition of ACTH release (211)

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The interactions between drugs and disease targets were visualized using Venny 2.1 to generate a Venn diagram, revealing 17 drug-disease targets (Figure 5C)

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Each participant completes an individual physician intake before treatment begins

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